RIP3 (Phospho-Ser227) Rabbit Polyclonal Antibody - BT-AP12295

RIP3 (Phospho-Ser227) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12295-20, BT-AP12295-50, BT-AP12295-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases| and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm| and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex| and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Research Areas: Cancer; Cell biology; Immunology; Signal transduction

Target Protein: RIPK3

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: RIP3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y572; Mouse: Q9QZL0; Rat: Q9Z2P5

Synonyms: RIP3;Ser227; Receptor-interacting serine/threonine-protein kinase 3; EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3

GeneID: Human: 11035; Rat: 246240

Research Use Only