Product Description

RLN2 Polyclonal Antibody

Catalogue Numbers: BS60533-50, BS60533-100

Sizes: 50µl, 100µl

Alternative Name: Prorelaxin H2; RLN2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P04090

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RLN2 polyclonal antibody detects endogenous levels of RLN2 protein.

Bioworld Molecular Weight: ~ 21 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of RLN2 polyclonal antibody at 1:500 dilution
Lane 1: Jurkat whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human RLN2

Conjugate: Unconjugated

Modification: Unmodified