Product Description

RNASE4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60511-50, BS60511-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RNase 4 and RNase 5/ang 1 are unique among the RNase A ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing. Rnase4 (ribonuclease, RNase A family 4) gene can produce 2 transcripts both encoding 148 amino acid proteins. Rnase 4 is a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 4 prefers poly(C) as a substrate and hydrolyzes 2', 3'-cyclic nucleotides, with a pH optimum near 8.0. mRNA encoding RNase 4 is detectable in human pancreas, lung, skeletal muscle, heart, kidney and placenta, liver represents the most abundant source.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Ribonuclease 4, RNase 4, RNASE4, RNS4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human RNASE4.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RNASE4 polyclonal antibody detects endogenous levels of RNASE4 protein.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P34096

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only