Product Description

RNF14 Polyclonal Antibody

Catalogue Numbers: BS65257-50, BS65257-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q9UBS8

Host: Rabbit

Reactivity: Human

Applications: WB,ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Background: ring finger protein 14(RNF14) Homo sapiens The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ARA54 Polyclonal Antibody detects endogenous levels of ARA54 protein.

Extra Notes: Western blot analysis of lysates from RAW264.7 cells, using RNF14 Antibody. The lane on the right is blocked with the synthesized peptide.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: RNF14; ARA54; HRIHFB2038; E3 ubiquitin-protein ligase RNF14; Androgen receptor-associated protein 54; HFB30; RING finger protein 14; Triad2 protein

Immunogen: The antiserum was produced against synthesized peptide derived from human RNF14. AA range:361-410

Conjugate: Unconjugated

Modification: Unmodified