Product Description

RNF52 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66579-50, MB66579-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Negatively regμlates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resμlting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regμlating nuclear transport.S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: RNF52, BRCA1-associated protein, BRAP2, Impedes mitogenic signal propagation, IMP, RING finger protein 52, Renal carcinoma antigen NY-REN-63

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human BRAP protein fragments expressed in E.coli.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of RNF52 protein.

Molecular Weight: ~ 56 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q7Z569

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only