RNF7 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-61633-60, E-AB-61633-120, E-AB-61633-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RNF7
Target Synonym: RNF7; CKBBP1; ROC2; SAG
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9UBF6
Background: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human RNF7 (NP_055060.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:20-1:50
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only