Rock-2 rabbit pAb - ES3388

Rock-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3388-50, ES3388-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008],

Alternate Name: ROCK2; KIAA0619; Rho-associated protein kinase 2; Rho kinase 2; Rho-associated; coiled-coil-containing protein kinase 2; Rho-associated, coiled-coil-containing protein kinase II; ROCK-II; p164 ROCK-2

Source: Rabbit

Applications: IF; WB; IHC; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunocytochemistry: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human ROCK2. AA range:691-740

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 165kD

Human Gene ID: 9475

Human SWISS Prot NO: O75116

Subcellular Location: Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic, and associated with actin microfilaments and the plasma membrane.

Research Use Only