Product Description

RON (9B6) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3143-50, MB3143-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q04912

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Ron is initially synthesized in the cells as a single-chain, pro-Ron precursor that is cleaved into the two active chains. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RON in HCC827 , HT-29 , HCT116 and BxPC-3Lysates using RON antibody.

Bioworld Molecular Weight: Calculated MW: 152 kDa; Observed MW: 152 kDa

Specificity: IgG1

Alternative Name: MST1R; PTK8; RON; Macrophage-stimulating protein receptor; MSP receptor; CDw136; Protein-tyrosine kinase 8; p185-Ron; CD136

Immunogen: Purified recombinant fragment of human RON (aa210-320) expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified