RORα rabbit pAb - ES3389

RORα rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3389-50, ES3389-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014],

Alternate Name: RORA; NR1F1; RZRA; Nuclear receptor ROR-alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; Retinoid-related orphan receptor-alpha

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human RORA. AA range:6-55

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 6095

Human SWISS Prot NO: P35398

Subcellular Location: Nucleus

Research Use Only