Product Description

ROR1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A3315-20, A3315-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Rat

Protein Weight: 104kDa

Observed Molecular Weight: 135kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 4919

SWISS: Q01973

Alternate Names: NTRKR1; dJ537F10.1; ROR1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Kinase, Tyrosine kinases, Neuroscience.

NCBI Alias: ROR1

Research Use Only