RPA2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24881-20, A24881-100
Citations, Manuals and MSDS Available upon request.
Background: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.Functions as component of the alternative replication protein A complex (aRPA) . aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human
Protein Weight: 29kDa/30kDa/38kDa
Observed Molecular Weight: 35kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6118
SWISS: P15927
Alternate Names: RPA2; REPA2; RP-A p32; RP-A p34; RPA32; RP-Ap32; RP-Ap34; replication protein A2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 IHC-P, 1:100 - 1:500 IF/ICC, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics & Nuclear Signaling, DNA Damage & Repair.
NCBI Alias: RPA2
Research Use Only