Rpb1 CTD (Phospho-Ser2) Rabbit Polyclonal Antibody - BT-AP12337

Rpb1 CTD (Phospho-Ser2) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12337-20, BT-AP12337-50, BT-AP12337-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the largest subunit of RNA polymerase II| the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition| this subunit| in combination with several other polymerase subunits| forms the DNA binding domain of the polymerase| a groove in which the DNA template is transcribed into RNA.

Research Areas: Epigenetics and nuclear signaling

Target Protein: POLR2A

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Rpb1 CTD

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P24928; Mouse: P08775

Synonyms: Rpb1 CTD;Ser2; DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; EC 2.7.7.6; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; EC 2.7.7.48

GeneID: Human: 5430; Mouse: 20020

Research Use Only