Product Description

RPGF4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34578-50, RA34578-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: domain:The DEP domain is involved in membrane localization independent from regulation by cAMP., domain:The N-terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2., function:Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2., similarity:Contains 1 DEP domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 Ras-GEF domain., similarity:Contains 2 cyclic nucleotide-binding domains., subunit:Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A., tissue specificity:Predominantly expressed in brain and adrenal gland. Isoform 2 is expressed in liver. Isoform 1 is expressed in liver at very low levels.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 111

Protein Molecular Weight (kDa): 111

Storage: -20°C/1 year

Human Gene ID: 11069

Human SwissProt Number: Q8WZA2

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only