Product Description

RPS19 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5907-50, BS5907-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ribosomal subunits are synthesized in the nucleus and mature 40S and 60S subunits are exported stoichiometrically into the cytoplasm. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. Ribosomal proteins have the ability to pass through the nu-clear envelope in the native state, making them the largest of the structures accommodated by the nuclear pore complexes. The nuclear export of ribosomal subunits is a unidirectional, saturable and energy-dependent process. Ribosomal Protein S19 (RPS19) is a 145 amino acids protein expressed in various human adμlt tissues, including bone marrow, peripheral blood, spleen, liver and nonhematopoietic tissues. RPS19 expression decreases during terminal erythroid differentiation, a deficiency of RPS19 blocks proliferation of immature erythroid progenitor cells altogether. Muta-tions in the RPS19 gene are linked with Diamond-Blackfan anemia (DBA), a congenital, hypo-plastic, red cell aplasia that occasionally presents with physical anomalies.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: 40S ribosomal protein S19

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 100-145 of Human RPS19.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RPS19 polyclonal antibody detects endogenous levels of RPS19 protein.

Molecular Weight: ~ 16 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P39019

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only