Product Description

RPS19 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91181-50, BS91181-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P39019(Human) Q9CZX8(Mouse) P17074(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IP,

All Applications: WB:1:500-1:1,000
IHC:1:50-1:200
IP:1:10-1:50

Background: Ribosomal subunits are synthesized in the nucleus and mature 40S and 60S subunits are exported stoichiometrically into the cytoplasm. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. Ribosomal proteins have the ability to pass through the nu-clear envelope in the native state, making them the largest of the structures accommodated by the nuclear pore complexes. The nuclear export of ribosomal subunits is a unidirectional, saturable and energy-dependent process. Ribosomal Protein S19 (RPS19) is a 145 amino acids protein expressed in various human adult tissues, including bone marrow, peripheral blood, spleen, liver and nonhematopoietic tissues. RPS19 expression decreases during terminal erythroid differentiation; a deficiency of RPS19 blocks proliferation of immature erythroid progenitor cells altogether. Muta-tions in the RPS19 gene are linked with Diamond-Blackfan anemia (DBA), a congenital, hypo-plastic, red cell aplasia that occasionally presents with physical anomalies.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RPS19 polyclonal antibody detects endogenous levels of RPS19 protein.

Bioworld Molecular Weight: 16 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RPS19 on Hela cell using anti-RPS19 antibody at 1/500 dilution.
Positive control:
Lane 1: CRC
Lane 2: MCF-7, Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-RPS19 antibody. Counter stained with hematoxylin.

Alternative Name: RPS19, 40S ribosomal protein S19, DBA, DBA1, HGNC:10402, Ribosomal protein S19, rps19, RS19, S19,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified