RRAD Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16047-60, E-AB-16047-120, E-AB-16047-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: RRAD
Target Synonym: GTP binding protein RAD; GTP-binding protein RAD; RAD; RAD; RAD1; RAS (RAD and GEM) like GTP binding 3; Ras associated with diabetes; Ras related associated with diabetes; REM3; RRAD
Research Areas: Cardiovascular, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P55042
Background: The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
Concentration: 0.2 mg/mL
Immunogen: Synthetic peptide of human RRAD
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only