RRM2 Polyclonal Antibody-BS7520

RRM2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS7520-50, BS7520-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P31350

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P IF/ICC IP,

All Applications: WB 1:500 - 1:1000
IHC-P 1:50 - 1:200
IF/ICC 1:50 - 1:200
IP 1:50 - :1200

Background: Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RRM2 polyclonal antibody detects endogenous levels of RRM2 protein.

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of HeLa cells, using RRM2 antibody at 1:1000 dilution., Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using RRM2 pAb at dilution of 1:100 (40x lens)., Immunofluorescence analysis of U2OS cells using RRM2 pAb at dilution of 1:100 (40x lens)., Immunoprecipitation analysis of 200 μg extracts of HeLa cells using 1 μg RRM2 antibody. Western blot was performed from the immunoprecipitate using RRM2 antibody at a dilution of 1:1000.

Alternative Name: R2; Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase M2 subunit; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RIR2_HUMAN; RR2; RR2M; RRM2

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RRM2 (NP_001025.1).

Conjugate: Unconjugated

Modification: Unmodified