Product Description

RRS1 (R286) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3932-50, BS3932-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: RRS1, also known as KIAA0112, ribosome biogenesis regμlatory protein homolog, regμlator of ribosome synthesis 1, ribosome biogenesis regμlatory protein RRS1 homolog or RRR, is a 365 amino acid protein belonging to the RRS1 family. RRS1 shows nucleolar localization and is involved in both ribosome biogenesis and chromosome congression. Recent studies indicate that in the absence of RRS1, cells experience mitotic delay due to abnormal spindle organization and chromosome alignment. The gene encoding RRS1 maps to human chromosome 8q13.1. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a resμlt of defects in specific genes that map to chromosome 8.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: Homolog of yeast ribosome biogenesis regμlator, Homolog of yeast ribosome biogenesis regμlatory protein RRS1, KIAA0112, OTTHUMP00000227420, Ribosome biogenesis regμlatory protein homolog, Ribosome biogenesis regμlatory protein RRS1 homolog, RRR, rrs1,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 255-307 of Human RRS1.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RRS1 (R286) polyclonal antibody detects endogenous levels of RRS1 protein.

Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15050

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only