RRS1 (R286) Polyclonal Antibody-BS3932

RRS1 (R286) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3932-50, BS3932-100

Sizes: 50µl, 100µl

Swiss-Prot: Q15050

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: RRS1, also known as KIAA0112, ribosome biogenesis regulatory protein homolog, regulator of ribosome synthesis 1, ribosome biogenesis regulatory protein RRS1 homolog or RRR, is a 365 amino acid protein belonging to the RRS1 family. RRS1 shows nucleolar localization and is involved in both ribosome biogenesis and chromosome congression. Recent studies indicate that in the absence of RRS1, cells experience mitotic delay due to abnormal spindle organization and chromosome alignment. The gene encoding RRS1 maps to human chromosome 8q13.1. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: RRS1 (R286) polyclonal antibody detects endogenous levels of RRS1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of RRS1 (R286) pAb at 1:1000 dilution
Lane 1: EC9706 whole cell lysate (10ug)
Lane 2: A375 whole cell lysate (10ug), Immunohistochemistry (IHC) analyzes of RRS1 (R286) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Homolog of yeast ribosome biogenesis regulator; Homolog of yeast ribosome biogenesis regulatory protein RRS1; KIAA0112; OTTHUMP00000227420; Ribosome biogenesis regulatory protein homolog; Ribosome biogenesis regulatory protein RRS1 homolog; RRR; rrs1;

Immunogen: Synthetic peptide, corresponding to amino acids 255-307 of Human RRS1.

Conjugate: Unconjugated

Modification: Unmodified