RSK1 p90 (6B9) Monoclonal Antibody-MB3071

RSK1 p90 (6B9) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3071-50, MB3071-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q15418

Host: Mouse

Reactivity: Human, Mouse, Monkey

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 83 kDa; Observed MW: 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p90RSK in COS7, 3T3, Jurkat, Hela and A549 lysates using p90RSK antibody., Immunoprecipitation analysis of RSK1 p90 in Hela lysates using p90RSK antibody.

Alternative Name: RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kinase alpha-1; S6K-alpha-1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAP

Immunogen: Purified recombinant human p90RSK protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified