RTKN Rabbit pAb - A6732

RTKN Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6732-20, A6732-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 63kDa

Observed Molecular Weight: 63kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 6242

SWISS: Q9BST9

Alternate Names: RTKN; rhotekin

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, G protein signaling, Small G proteins, Cell Biology Developmental Biology, Apoptosis.

NCBI Alias: RTKN

Research Use Only