RUBCN Monoclonal Antibody - BT-MCA4352

RUBCN Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4352-50, BT-MCA4352-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research Areas: Others

Target Protein: RUBCN

Clonality: Monoclonal

Clone ID: 4F5B5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: RUBCN

Immunogen: Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 108.6kDa

UniProt Accession: Q92622

Synonyms: SCAR15, RUBICON, KIAA0226

GeneID: 9711

Research Use Only