RUBIC Rabbit Polyclonal Antibody - RA34623

RUBIC Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34623-50, RA34623-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.290% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Run domain Beclin-1 interacting and cystein-rich containing protein (Rubicon) (Beclin-1 associated RUN domain containing protein) (Baron)

Applications: WB

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 9711

Protein MW (KDa): 105

SWISS: Q92622

Source: Rabbit

Research Use Only