Rubicon Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16652-20, A16652-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 109kDa
Observed Molecular Weight: 108kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9711
SWISS: Q92622
Alternate Names: SCAR15; RUBICON; KIAA0226; Rubicon
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Autophagy, Endocrine Metabolism, Cardiovascular, Heart.
NCBI Alias: RUBCN
Research Use Only