RUFY3 Rabbit pAb - A12896

RUFY3 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A12896-20, A12896-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Mouse, Rat

Protein Weight: 53kDa

Observed Molecular Weight: 56kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 22902

SWISS: Q7L099

Alternate Names: RIPX; SINGAR1; ZFYVE30; RUFY3

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, G protein signaling, Small G proteins.

NCBI Alias: RUFY3

Research Use Only