RUNX3 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29589-50, RA29589-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: runt related transcription factor 3 (RUNX3) Homo sapiens This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016], Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Alternate Names: RUNX3, AML2, CBFA3, PEBP2A3, Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEB Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. Molecular Weight: 44 Protein Molecular Weight (kDa): 44 Storage: -20°C/1 year Human Gene ID: 864 Human SwissProt Number: Q13761 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only