RYK Monoclonal Antibody-MB66969

RYK Monoclonal Antibody

Catalogue Numbers: MB66969-50, MB66969-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P34925

Host: Mouse

Reactivity: Human

Applications: WB, FC

All Applications: WB (1/500 - 1/1000), FC (1/10 - 1/50)

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of RYK protein.

Extra Notes: Western blot analysis of RYK expression in human lung (A) whole cell lysates.

Bioworld Molecular Weight: ~ 73 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: JTK5A; Tyrosine-protein kinase RYK

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RYK. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified