S100α6 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91197-50, BS91197-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P06703(Human) P14069(Mouse) P05964(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF, IHC, IP, , FC
All Applications: WB:1:1,000-1:5,000
ICC:1:100-1:500
IHC:1:50-1:200
FC:1:50-1:100
Background: Calcyclin, also known as Prolactin receptor-associated protein (PRA), growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: S100α6 polyclonal antibody detects endogenous levels of S100α6 protein.
Bioworld Molecular Weight: 10 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of S100 alpha 6 on different lysates using anti-S100 alpha 6 antibody at 1/1,000 dilution.
Positive control:
Lane 1: A431
Lane 2: Mouse lung, ICC staining S100 alpha 6 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: PRA, S100A6, 2A9, 5B10, CABP, CACY, Calcyclin, Growth factor inducible protein 2A9, Growth factor-inducible protein 2A9, MLN 4, MLN4, OTTHUMP00000015472, OTTHUMP00000015473, PRA, PRAGrowth factor inducible protein 2A9, Prolactin receptor associated protein, Prolactin receptor-associated protein, Protein S100 A6, Protein S100-A6, S100 A6, S100 calcium binding protein A6 (calcyclin), S100 calcium binding protein A6, S100 calcium-binding protein A6, S100A6, S10A6,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified