S100 β Polyclonal Antibody - RA34686

S100 β Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA34686-50, RA34686-100 Citations, Manuals and MSDS Available upon request. Background: S100 calcium binding protein B (S100B) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. Alternative Names: Protein S100-B (S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B) ; YM3476 Applications: WB; IHC-p; IF (paraffin section) Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 6285 Protein MW (KDa): 11 SWISS: P04271 Source: Rabbit Research Use Only