S100 rabbit pAb - ES20636

S100 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20636-50, ES20636-100

Citations, Manuals and MSDS Available upon request.

Background: S100 calcium binding protein A1 (S100A1) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008],

Alternate Name: Protein S100-A1 (S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1)

Source: Rabbit

Applications: WB; IHC; IF

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse

Immunogen: Recombinant Protein of S100

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 15kD

Human Gene ID: 6271

Human SWISS Prot NO: P23297

Subcellular Location: Cytoplasm. Sarcoplasmic reticulum. Mitochondrion.

Research Use Only