Product Description

S100A10 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91193-50, BS91193-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P60903(Human) P08207(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200

Background: The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: S100A10 polyclonal antibody detects endogenous levels of S100A10 protein.

Bioworld Molecular Weight: 11 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of S100A10 on human lung lysates using anti-S100A10 antibody at 1/1,000 dilution., Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-S100A10 antibody. Counter stained with hematoxylin.

Alternative Name: S100A10, 42C, AA409961, AL024248, Annexin II ligand, Annexin II ligand, calpactin I, light polypeptide, Annexin II tetramer (AIIt) p11 subunit, Annexin II, light chain, ANX2L, ANX2LG, Ca[1], CAL12, CAL1L, Calpactin I light chain, Calpactin I, p11 subunit, Calpactin-1 light chain, Cellular ligand of annexin II, CLP11, GP11, MGC111133, Nerve growth factor-induced protein 42C, OTTHUMP00000015269, OTTHUMP00000015270, p10, p10 protein, p11, Protein S100 A10, Protein S100-A10, S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)), S100 calcium binding protein A10 (calpactin), S100 calcium binding protein A10, S100 calcium-binding protein A10, S100a10, S10AA,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified