S100A4 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-40458-60, E-AB-40458-120, E-AB-40458-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: S100A4
Target Synonym: 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; S100 calcium binding protein A4; S100a4
Research Areas: Cardiovascular, Signal Transduction, Cancer
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P26447
Background: S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Concentration: 1.2mg/ml
Immunogen: Recombinant Human Protein S100-A4 protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification Method: Antigen Affinity Purification
Dilution: WB:1:500-1000 IHC 1:100-1:400
Calculated MW: 11kDa
Observed MW: 11kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only