S12A1 Rabbit Polyclonal Antibody - RA34636

S12A1 Rabbit Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA34636-50, RA34636-100 Citations, Manuals and MSDS Available upon request. Background: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1：500-2000 Applications: WB Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 6557 SWISS: Q13621 Source: Rabbit Research Use Only