Product Description

S1P/Subtilisin Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65838-50, BS65838-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regμlated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regμlates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: kexin isozyme 1, KIAA0091, MBTP1_HUMAN； MBTPS1, membrane bound transcription factor peptidase, site 1, MGC138711, MGC138712, PCSK8, S1P, S1P endopeptidase, Site 1 protease, SKI 1, SKI1, Subtilisin isozyme 1, Subtilisin/kexin isozyme 1.  

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human S1P/Subtilisin isozyme 1:861-960/1052

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: S1P/Subtilisin Polyclonal Antibody detects endogenous levels of S1P/Subtilisin protein.

Molecular Weight: ~126 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -11°C long term. Avoid freeze-thaw cycles.

SwissProt: Q14703

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only