Product Description

S26A5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29619-50, RA29619-100

Citations, Manuals and MSDS Available upon request.

Background: solute carrier family 26 member 5 (SLC26A5) Homo sapiens This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: Prestin (Solute carrier family 26 member 5)

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 375611

Protein MW (KDa): 81

SWISS: P58743

Source: Rabbit

Research Use Only