S2P rabbit pAb - ES6518

S2P rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6518-50, ES6518-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],

Alternate Name: MBTPS2; S2P; Membrane-bound transcription factor site-2 protease; Endopeptidase S2P; Sterol regulatory element-binding proteins intramembrane protease; SREBPs intramembrane protease

Source: Rabbit

Applications: WB; IP; IF; ELISA

Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 51360

Human SWISS Prot NO: O43462

Subcellular Location: Membrane; Multi-pass membrane protein. Cytoplasm.

Research Use Only