Product Description

SAF-B1 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66523-50, MB66523-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecμlar assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing.Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription.Thereby acts as a negative regμlator of cell proliferation, When associated with RBMX, binds to and stimμlates transcription from the SREBF1 promoter (By similarity).

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IF/ICC, ChIP

Alternate Names: HAP, HET, SAFB1, Scaffold attachment factor B1, SAF-B, SAF-B1, HSP27 estrogen response element-TATA box-binding protein, HSP27 ERE-TATA-binding protein

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Purified recombinant human SAFB1 protein fragments expressed in E.coli.

Dilution: WB (1/500 - 1/1000), IF/ICC (1/50 - 1/100), ChIP (1/10 - 1/50)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of SAF-B1 protein.

Molecular Weight: ~ 130 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15424

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only