SAFB1 Mouse Monoclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA11972-50, RA11972-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: scaffold attachment factor B (SAFB) Homo sapiens This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript v Reactivity: Human Host: Mouse Applications: WB, ICC Alternate Names: DKFZp779C1727, glutathione S transferase fusion protein, HAP, HET, HSP27 ERE TATA binding protein, HSP27 ERE-TATA-binding protein, HSP27 estrogen response element-TATA box-binding protein, SAF B, SAF-B1, SAFB 1, SAFB, SAFB1, SAFB1_HUMAN, scaffold attachment factor B1. Clonality: Monoclonal Dilution: wb 1:1000 icc 1:200 Storage: -20°C/1 year Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Human Gene ID: 6294 Protein Molecular Weight（KDa): 130 Molecular Weight: 130 Research Use Only