SAP 49 Polyclonal Antibody - BT-AP08125

SAP 49 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08125-20, BT-AP08125-50, BT-AP08125-100

Citations, Manuals and MSDS Available upon request.

Background: SF3B4 encodes one of four subunits of the splicing factor 3B. The splicing factor 3b subunit 4 encoded by SF3B4 cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: SF3B4

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: SAP 49 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 44386

UniProt Accession: Human: Q15427; Mouse: Q8QZY9; Rat: Q6AYL5

Synonyms: SF3B4; SAP49; Splicing factor 3B subunit 4; Pre-mRNA-splicing factor SF3b 49 kDa subunit; SF3b50; Spliceosome-associated protein 49; SAP 49

GeneID: Human: 10262; Mouse: 107701; Rat: 295270

Research Use Only