Product Description

SAR1B Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61634-50, BS61634-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: There are a number of components involved in the secretory pathway of cells. Vesicμlar traffic within the early secretory pathway is mediated by COPI- and COPII-coated vesicles. The COPII vesicle coat protein promotes the formation of endoplasmic reticμlum (ER) derived transport vesicles that carry secretory proteins to the Golgi complex. The SAR1 gene encodes two isoforms, Sar1a and Sar1B, in mammalian cells. These proteins are low-molecμlar-weight GTPases, which are essential for the formation of transport vesicles from the ER. Mutations in the SAR1 gene resμlt in Anderson’s disease (and/or chylomicron retention disease CMRD), a rare, autosomal recessive lipid malabsorption disorder characterized by chronic diarrhea, failure to thrive and hypocholesterolemia in childhood.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: GTP-binding protein B, GTBPB, GTP-binding protein SAR1b, SAR1B, SARA2, SARB

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human SAR1B.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SAR1B polyclonal antibody detects endogenous levels of SAR1B protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y6B6

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only