Product Description

Sarcoglycan-β (V136) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3518-50, BS3518-100

Sizes: 50µl, 100µl

Swiss-Prot: Q16585

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Sarcoglycan-β (V136) polyclonal antibody detects endogenous levels of Sarcoglycan-β protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Sarcoglycan-β (V136) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 35 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Beta-sarcoglycan; β-sarcoglycan; Beta-SG; SG-β; SGβ; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b; SGCB

Immunogen: Synthetic peptide, corresponding to amino acids 102-158 of Human Sarcoglycan-β.

Conjugate: Unconjugated

Modification: Unmodified