SARS-CoV-2 N Protein Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS65885-50, BS65885-100
Swiss-Prot: P0DTC9
Host: Rabbit
Applications: WB
All Applications: WB=1:500-2000
Background: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purification and Purity: affinity purified by Protein A
Storage and Stability: Store at 4°C short term. Aliquot and store at -58°C long term. Avoid freeze-thaw cycles.
Specificity: SARS-CoV-2 N protein Polyclonal Antibody detects endogenous levels of SARS-CoV-2 N protein protein.
Bioworld Molecular Weight: ~46 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein.
Immunogen: Recombinant SARS-CoV-2 Nucleocapsid Protein
Conjugate: Unconjugated
Modification: Unmodified