SARS-CoV Spike Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A20605-20, A20605-100
Citations, Manuals and MSDS Available upon request.
Background: The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: SARS-CoV
Protein Weight: 139kDa
Observed Molecular Weight: 200kDa
Immunogen: Synthetic peptide
GeneID: 1489668
SWISS: P59594
Alternate Names: E2; SARS-CoV Spike
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: Spike
Research Use Only