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SASH1 Polyclonal Antibody - E-AB-53327

SASH1 Polyclonal Antibody - E-AB-53327

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SASH1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53327-60, E-AB-53327-120, E-AB-53327-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: SASH1

Target Synonym: 2500002E12Rik; dJ323M4; dJ323M4.1; KIAA0790; PEPE 1; PEPE1; Proline glutamate repeat containing protein; Proline-glutamate repeat-containing protein; RP3 323M4.1; SAM and SH3 domain containing 1; SAM and SH3 domain containing protein 1; SAM and SH3 domain-containing protein 1; SASH 1; Sash1; SASH1

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O94885

Background: This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients.

Concentration: 0.78 mg/mL

Immunogen: Synthetic peptide of human SASH1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Calculated MW: 137 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only