Product Description

SAT1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67353-50, BS67353-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Spermidine/spermine N1-acetyltransferase 1 (SAT1) is a key enzyme in polyamine metabolism. It acts by acetylating spermidine and spermine using acetyl-coenzyme A (CoA), which alters their charge and facilitates their secretion. SAT1 activity is tightly controlled in cells, but increases quickly by excess polyamines. Its activity can also be induced by a number of other stimμli, such as oxidative stress, heat shock, insμlin-like growth factor-I, and cytotoxins. Research studies have found that SAT1 is overexpressed in glioblastoma mμltiforme (GBM), which suggest that SAT1 may be a potential therapeutic target for GBM.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: SAT, Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, Spermidine/spermine N(1)-acetyltransferase 1, SSAT, SSAT-1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human SAT1. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/2000)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of SAT1 protein

Molecular Weight: ~ 23 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P21673

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only