Product Description

SATB2 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16935-50, BZ16935-100

Swiss-Prot: Q9UPW6

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 83 kDa; Observed MW: 83 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SATB2 in HT-1080 lysates using SATB2 antibody.

Alternative Name: GLSS; SATB family member 2; SATB homeobox 2; SATB2; Special AT rich sequence binding protein 2

Immunogen: A synthesized peptide derived from human SATB2

Conjugate: Unconjugated

Modification: Unmodified