Product Description

SC6A4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29668-50, RA29668-100

Citations, Manuals and MSDS Available upon request.

Background: solute carrier family 6 member 4 (SLC6A4) Homo sapiens This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: Sodium-dependent serotonin transporter (5HT transporter;5HTT;Solute carrier family 6 member 4)

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 6532

Protein MW (KDa): 69

SWISS: P31645

Source: Rabbit

Research Use Only