Product Description

SCD Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60618-50, BS60618-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters. SCD plays a major role in the triacylglycerol and phospholipid secretion process and in mechanisms of cellμlar cholesterol homeostasis. It is subject to rapid turnover in the cell and, as such, represents a model for studying selective degradation of short-lived proteins of the ER. SCD is also an important regμlator of membrane fluidity. An increase in expression levels of SCD is observed in cells which are induced to differentiate into adipocytes and in certain tumor cell lines. Due to gene duplication events, the number of genes in the SCD family differs between species. Their expression patterns are affected by the level of unsaturated fatty acids in the diet of the animal.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Acyl-CoA desaturase, Delta(9)-desaturase, Delta-9 desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase, SCD

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human SCD

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: SCD polyclonal antibody detects endogenous levels of SCD protein.

Molecular Weight: ~ 42 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O00767

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only