Product Description

SCD1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11571-50, MB11571-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O00767

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Stearyl-CoA desaturase that utilizes O2 and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation . Plays an important role in body energy homeostasis . Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 42 kDa; Observed MW: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SCD1 in Hela lysates using SCD1 antibody., Immunocytochemistry analysis of SCD1 in Hela using SCD1 antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human lung cancer using SCD1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: SCD1; FADS5; SCDOS; MSTP008

Immunogen: Recombinant protein of human SCD1

Conjugate: Unconjugated

Modification: Unmodified