Product Description

SCML2 Polyclonal Antibody

Catalogue Numbers: BS62478-50, BS62478-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9UQR0

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:500~1000

Background: In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: SCML2 polyclonal antibody detects endogenous levels of SCML2 protein.

Extra Notes: Western blot (WB) analysis of SCML2 polyclonal antibody at 1:500 dilution
LaneA:HEK293T whole cell lysate
LaneB:K562 whole cell lysate
LaneC:A549 whole cell lysate
LaneD:H1792 whole cell lysate

Bioworld Molecular Weight: ~ 77,93 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Sex comb on midleg-like protein 2; SCML2

Immunogen: Synthetic peptide, corresponding to Human SCML2.

Conjugate: Unconjugated

Modification: Unmodified