Product Description

SCML2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62478-50, BS62478-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Sex comb on midleg-like protein 2, SCML2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human SCML2.

Dilution: WB: 1:500~1000

Purification: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Specificity: SCML2 polyclonal antibody detects endogenous levels of SCML2 protein.

Molecular Weight: ~ 77, 93 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UQR0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only