SCN11A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12863-60, E-AB-12863-120, E-AB-12863-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: SCN11A
Target Synonym: hNaN; NaN; NAV1.9; Peripheral nerve sodium channel 5; PN 5; PN5; SCN 11A; SCN 12A; Scn11a; SCN12A; SCNBA; Sensory neuron sodium channel 2; SNS 2; SNS2; Sodium channel protein type 11 subunit alpha; Sodium channel protein type XI subunit alpha; Sodium channel voltage gated type XI alpha; Sodium channel voltage gated type XI alpha polypeptide; Sodium channel voltage gated type XI alpha subunit; Sodium channel voltage gated type XII alpha polypeptide; Voltage gated sodium channel Nav1.9; Voltage gated sodium channel subunit alpha Nav1.9; Voltage-gated sodium channel subunit alpha Nav1.9
Research Areas: Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9UI33
Background: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human SCN11A
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only